Understanding potential side effects
including those that may show up in laboratory blood tests:
decreased white blood cell counts
increased liver function tests
muscle and bone pain
tiredness
decreased red blood cell counts
nausea
decreased potassium levels in your blood
decreased appetite
abnormal electrocardiogram (QTc [corrected QT interval] prolonged)
decreased platelet counts
constipation
These are not all the possible side effects of VEPPANU
If you experience side effects while on treatment, it’s important to talk to your doctor.
They may decrease your dose, temporarily stop, or completely stop treatment.
97
%
of people taking VEPPANU
did not discontinue due to an adverse reaction
of people
discontinued
VEPPANU
of people
needed dose
interruptions
of people
needed dose
reductions*
*Dose reductions of fulvestrant were not permitted.
Have heart failure or heart rhythm problems, including QTc prolongation, and long QTc syndrome
VEPPANU can cause changes in the electrical activity of your heart and may increase your risk of abnormal heart rhythm problems, and sudden death. Your doctor will check your heart with a test called an electrocardiogram and check your blood potassium and magnesium levels before and as needed during treatment with VEPPANU
Have low blood levels of potassium or magnesium
Are pregnant or plan to become pregnant. VEPPANU can harm your unborn baby
VEPPANU may affect fertility in males and in females who are able to become pregnant. Use effective birth control (contraception) during treatment with VEPPANU and for 2 weeks after the last dose. If you’re able to become pregnant, your doctor may do a pregnancy test before starting treatment with VEPPANU. Tell your doctor right away if you become pregnant or think you may be pregnant during treatment with VEPPANU
Share a list of your current medications, vitamins, and herbal supplements with your doctor and ask about possible interactions.
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VEP_BC-26084